Innovative Brizio Basi technology in the pharmaceutical sector: a castle of plates inside a lyophilizer chamber with automatic positioning, facing an automatic loading-unloading system through a door named “pizzadoor”.
Brizio Basi continues to advance pharmaceutical innovation with lyophilization solutions that combine precision, automation, and process safety.
One of the most notable technological developments is the integration of a castle of plates inside the chamber of the lyophilizer, paired with an automatic loading and unloading system operating through a specialized access door known as the “pizzadoor.”
This configuration has been engineered to address key challenges in pharmaceutical freeze-drying, where product integrity, process control, and efficiency are paramount.
Castle of plates: optimized thermal exchange and process uniformity
The castle of plates is an internal structure designed to accommodate trays in a multi-level arrangement. Each plate is equipped with channels for controlled heating and cooling fluids, enabling precise thermal exchange across all trays.
Automatic positioning mechanism: intelligent tray management
The system features automatic positioning of the plates, driven by an integrated control logic that aligns the internal castle precisely to the loading level. This mechanism enables full automation of the product handling phase and reduction of operator intervention inside critical environments.
These unique systems allow automatic loading and unloading of trays without manual handling. The pizzadoor operates in coordination with robotic or conveyor systems external to the lyophilizer.
Brizio Basi designs and manufactures turnkey systems entirely in-house, ensuring control over every stage of engineering, construction, and validation. This proprietary approach allows customization to specific production requirements and regulatory standards.
